I use several different house systems depending on the location of the chart being made. if the person is born above the arctic circle, for example, i will use Porphory so that the houses don't come out so lop-sided. usually, i flip back and forth between Placidous and Koch though I prefer Koch for what I intuitively sense as a more "realisitic" system than the more "idealistic"Placidous; again, this is validated by a feeling rather than by any measure of science.

What is now Uranian Astrology is based on the work of Alfred Witte, which changed rapidly while he was still alive, and which has changed a lot since his death (in 1941). His objective was to sort the nonsense out of astrology (like Kepler and Gauquelin wanted to do) and just use what really works, and as a result he did lots of daily practical research.
He was hounded by the Gestapo in Nazi Germany, and committed suicide when, some claim, he knew he was about to be arrested, and maybe the astrology told him what would come after that, or maybe he knew what happened to other people arrested by the Nazis.
His work was continued by one of his most enthusiastic students, Ludwig Rudolph, who published Witte's ideas, who was also harassed by the Nazis, and who ended up in a concentration camp, which he lived through and survived.
While Rudolph was in the concentration camp, Reinhold Ebertin took the work, cut out the extra planets that the Nazis didn't like (Witte had been harassed for proposing extra planets), and presented what was left as Cosmobiology, first popularized in the Nazi era.
Surprise! Rudolph survived the concentration camp until after the Nazis were defeated, and when after he was released and free again, he challenged Ebertin to acknowledge where his methods (including the 90-degree dial Uranian is famous for) came from, and a law suit followed.
The older forms of Uranian astrology used house systems much more, and they were gradually abandoned by the German astrologers who did the hard-core research... in favor of just midpoints and 16th harmonic aspects (which include conjunctions, squares, oppositions, semisquares and sesquisquares/quadrates as well as 22.5 degrees and its multiples. Later on, French astrologer Michel Gauquelin, while not a Uranian astrology, also hinted that the houses had problems. These were astrological scientists, who put the methods to the test, to weed out the fuzzy stuff.
A most recent, pragmatic, research-focused Uranian astrologer is Ruth Brummund, now in her 80s but still sorting the silliness and gray areas out of astrology.
Backtracking, Hans Niggemann, long popular in the USA, brought the older Uranian materials to the USA, translated some of the German texts, and popularized the Uranian house systems. Much of his translated material was actually written in German by Hermann Lefelt and Ilse Schnitzler and published in Germany in the 1940s and 1950s. While Americans were using emulating the Niggemann translations years later, the Germans kept doing more and more research, and refining the system. Ruth Brummund was one of the leaders in doing this.
For more information you can visit the Uranian Institute website, where there are lessons on how to do Uranian Astrology as the more recent research- and scientifically-oriented Uranian astrologers do it.